Before you do, you should know why you do that and what you want to get!
I give a example of myself. I am in a group which working on crystallography and cryo-EM. We see the virus particals and constracted the whole virus particals, especially the surface. After that, we need to study the protein on the surface. If it have 10 proteins, then try to identify all these proteins and solve its crystal structure, after that, build the molde in cryo-EM structure. I mean, you know, we can not do all the proteins even we can determine all the genes. Protein is much more complicated than gene. But before we really started to study proteinome, we should think about what we want to know,. If you just go and see, woo, it is very hard to draw some conclusions in this area.作者: orangecake 时间: 2012-11-30 16:32
蛋白质组学现在看来只能作为一种技术来被生命科学家应用 而一个生命科学界的主流问题就是 illucidate the mechanism how alterations in genotype results in the veriation in phenotype, 换句话说，就是要做功能鉴定 现在这个观点已经被广泛的接受 最典型的例子就是现在纯做蛋白质组学方面的研究发不了点数太高的paper 单纯的分析基因表达量的多少或者蛋白质表达量的多少，实际上对于功能学研究起不了多大作用 我现在的想法是能不能利用蛋白质组学进行一些信号通路方面的研究 当然 也包括其他分子生物学的研究手段结合在一起分析 作者: 98776langtao 时间: 2012-11-30 16:48
蛋白质组学现在看来只能作为一种技术来被生命科学家应用
蛋白质组学现在看来只能作为一种技术来被生命科学家应用 而一个生命科学界的主流问题就是 illucidate the mechanism how alterations in genotype results in the veriation in phenotype, 换句话说，就是要做功能鉴定 现在这个观点已经被广泛的接受 最典型的例子就是现在纯做蛋白质组学方面的研究发不了点数太高的paper 单纯的分析基因表达量的多少或者蛋白质表达量的多少，实际上对于功能学研究起不了多大作用 我现在的想法是能不能利用蛋白质组学进行一些信号通路方面的研究 当然 也包括其他分子生物学的研究手段结合在一起分析作者: sunshine039 时间: 2012-11-30 16:49
