牛奶中的确含有IGF-1。用巴氏消毒法(75摄氏度,45秒)消毒不能使牛奶中的IGF-1变性,但是在高温消毒后(121度,5分钟)就检测不到IGF-1的存在了(Collier et al., 1991)。蒙牛的“特仑苏”牛奶采用的是超高温瞬间灭菌消毒法(135-150度,4-15秒),2006年韩国有研究称用超高温瞬间法(130°C,2秒)灭菌的奶粉中,IGF-1的含量未见显著减少(Kang et al., 2006)。
新生儿是比较特殊的一段时期,可以从食物中完整地吸收一些蛋白质。但是实验表明,即使用药理学浓度的IGF-1喂养新生儿,也不能使血液中IGF-1的浓度发生变化,用同位素标记法直接测量发现,从新生儿肠道吸收的IGF-1的量可以忽略(Donovan and Odle, 1994; Odle et al., 1996; Burrin, 1997; Burrin et al, 1997;Donovan et al, 1997)。
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Renehan AG et al (2004) Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 363, 1346–1353作者: isabel 时间: 2009-2-15 03:32